Frequently asked questions

BioSynCare is a science-backed cognitive-entrainment wellness platform built from published research, 20+ years of practitioner experience, and a commitment to honest claims. It combines binaural beats, monaural beats, isochronic tones, guided breathing, symmetry patterns, Martigli waves, and audio-visual session design into structured protocols.
We are a small independent team, and that is exactly why we care about being precise, responsive, transparent, and directly accountable.
BioSynCare is a wellness platform, not a diagnostic or treatment service. We use stronger language where the evidence is stronger, and more cautious language where the research is still emerging or indirect.

Quick orientation

What BSC is
A structured cognitive-entrainment platform that combines entrainment audio, breathing guidance, visual rhythm, and sound design into full sessions.
How to get the best result
Use stereo headphones whenever you can, pick a goal that matches your current state, and repeat sessions long enough for your nervous system to learn the routine.
Safety and scope
BSC is for wellness and self-regulation support. It primarily uses rhythmic audio and may include gentle breathing-style visual guidance rather than rapid flashing or strobe-like visuals. If you have epilepsy, seizure-related conditions, photosensitive epilepsy, or other relevant medical conditions, check with a clinician first.
How we speak about evidence
Stress, attention, pain support, and autonomic regulation have stronger support than more exploratory areas like low mood or migraine comfort, so we label presets by evidence strength.
Selected evidence behind the platform
BioSynCare is built on established methods, but not every outcome has the same strength of evidence. These references show both the supporting literature and the reason we keep our claims disciplined.
Auditory entrainment
Meta-analytic support for improved cognition, reduced anxiety, and lower pain perception.
Garcia-Argibay et al. · 2019 · Psychological Research
View on PubMed
Slow breathing and HRV
Voluntary slow breathing increases vagally mediated heart rate variability.
Laborde et al. · 2022 · Neuroscience & Biobehavioral Reviews
View on PubMed
Attention and memory
The cognition literature is mixed but promising. Meta-analytic work suggests binaural-beat interventions can improve attention and memory in at least some contexts, which supports BSC's focus-oriented protocols.
Basu & Banerjee · 2023
View on PubMed
Pain support
A 2023 review and meta-analysis found sensory neural entrainment helpful for pain-related outcomes, with alpha protocols more relevant for acute pain and theta protocols more relevant for chronic pain support.
Maddison et al. · 2023
View on PubMed
HRV and long-term resilience
Higher heart-rate variability is associated with lower all-cause mortality risk. We do not claim to extend lifespan, but this is part of the rationale for framing resonance breathing as a resilience practice.
Jarczok et al. · 2022
View on PubMed
Why we grade our claims
Contradictory entrainment results, methodological variation, and limited generalizability.
Ingendoh et al. · 2023 · PLOS ONE
View on PubMed

Everything you need to know about BioSynCare, how it works, and what makes it different.

Getting started

BioSynCare is an audio-visual wellness app that uses brainwave entrainment — binaural beats, monaural beats, isochronic tones, guided breathing, colored noises, and soundscapes — combined with proprietary techniques like Martigli waves, symmetry patterns, and panning dynamics. Sessions are designed as structured cognitive-entrainment protocols, not libraries of isolated tones.
Stereo headphones are strongly recommended. Binaural beats work by sending slightly different frequencies to each ear, so your brain needs separate channels to perceive the frequency difference. Monaural beats, isochronic tones, and soundscapes still work through speakers, but the full experience requires headphones.
BioSynCare runs on the web (any modern browser), on iPhone through the App Store, and on Android through Google Play. The same session architecture works across all platforms.
No. BioSynCare is designed for wellness and self-regulation support. It does not diagnose, treat, cure, or prevent disease. It primarily uses rhythmic audio and may include gentle breathing-style visual guidance. It is not designed around rapid flashing or strobe-like visuals. If you have epilepsy, seizure-related conditions, photosensitive epilepsy, or other health concerns, please consult your doctor before using brainwave-entrainment technology.
Yes. BioSynCare offers a free tier with access to core presets and features. The Premium tier unlocks the full preset library, Seraphony AI, and additional capabilities.
BioSynCare's breathing protocols visually and audibly guide your respiration rate. Many sessions target cardiorespiratory resonance (~6 breaths per minute) for vagal tone optimization, with gradual pacing that starts at a comfortable rate and slows over the session duration.

Methods and features

Binaural beats occur when two slightly different frequencies are played in each ear. Your brain perceives a third, phantom frequency equal to the difference — called the binaural beat. This triggers a subcortical frequency-following response that can help guide your brain toward specific states like relaxation, focus, or sleep.
Monaural beats are created by mixing two tones before they reach the ear, producing a clearly audible amplitude modulation. Unlike binaural beats, they do not require headphones, but headphones still improve the experience. BioSynCare uses Martigli-modulated monaural beats that synchronize with breathing guidance for a deeper effect.
Isochronic tones are evenly spaced, sharply pulsed tones that turn on and off at a regular rate. They create a strong rhythmic stimulus that entrains brain activity through the cortical auditory pathway. BioSynCare extends isochronic techniques through its symmetry voice architecture, which adds programmable melodic-rhythmic patterns for cognitive engagement.
Cognitive entrainment is BioSynCare's approach to brainwave stimulation. Instead of relying on a single technique, it coordinates audio, visual rhythm, breathing guidance, and timing structure into an integrated protocol. This engages both the subcortical frequency-following system (via beats) and the cortical attentional system (via symmetry patterns), creating a dual-layer entrainment effect.
Martigli waves are a BioSynCare-proprietary technique: tones whose frequency oscillates in a breathing-synchronized contour, creating organic, 'living' sound that moves with your respiration. When combined with binaural beats (Martigli-Binaural), they create a warm, breath-responsive experience unique to BioSynCare.
Symmetry voices are programmable rhythmic-melodic patterns based on permuted note sequences. They target the cortical attentional system through controlled predictability — creating micro-reward cycles of prediction, confirmation, and reset. The permutation function (shuffle, rotate, reverse, identity) controls cognitive engagement level without changing frequencies.
Seraphony is BioSynCare's AI agent that generates personalized session presets on demand. It considers your stated goals, preferred duration, and desired stimulation style, then creates a new preset grounded in BioSynCare's evidence-mapped protocol architecture.
Rooms are a collaborative feature that lets multiple people run the same session in real-time sync. A host creates a room, selects a preset, and participants join and experience the session together — useful for group meditation, wellness workshops, or shared practice sessions.

Evidence, outcomes, and limits

BioSynCare presets are organized into five evidence-graded groups: Heal (stronger wellness support), Support (emerging, mixed, or more indirect evidence), Perform (focus, work, creativity), Indulge (experiential, recreational), and Transcend (meditation, contemplation). The point is not just organization; it is claim discipline.
Yes, with important nuance. Garcia-Argibay et al. (2019) reported a medium, statistically significant effect of binaural beats on cognition, anxiety, and pain-related outcomes, and slow breathing has consistent support for autonomic regulation. At the same time, later reviews note that parts of the literature remain heterogeneous. BioSynCare treats that as a reason for precision, not hype.
BioSynCare combines peer-reviewed scientific foundations, long-term guided practice, software architecture, sound design, and day-to-day product engineering. Renato Fabbri, PhD, brings more than 20 years of practice and hundreds of guided sessions, while Riccardo Berti contributes core application development, product iteration, operations, and musical sensitivity.
BioSynCare is not a medical treatment, and those use cases do not all sit on equally strong evidence. Anxiety support is the best-supported of the three. Low mood and migraine-prone states are handled more cautiously as support-oriented goals, with gentler session design and more conservative wording. If you are dealing with clinical depression, migraines, or any medical condition, BSC should complement, not replace, professional care.
BioSynCare's resonance-breathing protocols support heart-rate variability (HRV), a widely used marker of autonomic resilience. Higher HRV is associated with lower all-cause mortality risk, which is one reason we frame BSC as a resilience and vitality practice. We do not claim to extend lifespan; we claim to support the kinds of physiological conditions linked to healthier aging.
Because it is best understood like exercise or sleep hygiene: not as a cure-all, but as a practice that can influence many outcomes because it works through foundational regulatory processes. Rhythmic sensory support, slower breathing, and structured session pacing can all affect how people settle, focus, recover, and rest.
Need a human answer?
If your question is about access, billing, collaboration, or anything the FAQ does not cover, email us and we will route it personally.
Email BioSynCare
riccardo@aeterni.org